IONIC LIQUID FORMS OF THE ANTIMALARIAL LUMEFANTRINE IN COMBINATION WITH LFCS TYPE IIIB LIPID-BASED FORMULATIONS PREFERENTIALLY INCREASE LIPID SOLUBILITY, IN VITRO SOLUBILIZATION BEHAVIOR AND IN VIVO EXPOSURE

Lipid based formulations (LBFs) are commonly employed to enhance the absorption of highly lipophilic, poorly water-soluble drugs.However, the utility of LBFs can be limited by low drug solubility in the formulation.Isolation of ionizable drugs as low melting, lipophilic salts or ionic liquids (ILs) provides one means to enhance drug solubility in L

Background: Congenital hearing loss is remarkably heterogeneous, with over 130 deafness genes and thousands of variants, making for innumerable genotype/phenotype combinations.Understanding both the pathophysiology of hearing Acrylic Fridge Magnet loss and molecular site of lesion along the auditory pathway permits for significantly individualized

Objectives This article will attempt to analyse securitisation theory to explore the discursive features of cyber security, using a multi-actor approach that considers the role of state and non-state actors in the creation and management of cyber security discourses.Material and methods The paper aims to assess the contribution of securitization th

Tapis kelapa (Coconut filter) as natural fiber, in this time its resources very copius but no longer be exploited and thrown off hand as waste though in fact its used for other material dissimilar inovatif and high economic valuable that is as one of natural fiber alternative to be composite.The objective of this research is to investigate the beha

Abstract This study introduces a novel framework for dynamic reconnaissance operations using Unmanned Aerial Vehicle (UAV) swarms, designed to adapt CARDIO FLOW in real time to changes in mission parameters and UAV availability.Unlike traditional models that assume static operational conditions, our approach distinguishes between two key categories